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Article

The impact of assortative mating, participation bias and socioeconomic status on the polygenic risk of behavioural and psychiatric traits.

Nature human behaviour - 1 May 2024

Cabrera-Mendoza Brenda, Wendt Frank R, Pathak Gita A, Yengo Loic, Polimanti Renato

Abstract excerpt

To investigate assortative mating (AM), participation bias and socioeconomic status (SES) with respect to the genetics of behavioural and psychiatric traits, we estimated AM signatures using gametic phase disequilibrium and within-spouses and within-siblings polygenic risk score correlation analyses, also performing a SES conditional analysis. The cross-method meta-analysis identified AM genetic signatures for...

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Identifiers

PMID: 38366106
DOI: 10.1038/s41562-024-01828-5
PMCID: PMC11161911

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