Posttranscriptional regulation of retroviral gene expression: primary RNA transcripts play three roles as pre‐ mRNA , mRNA , and genomic RNA

Abstract excerpt

After reverse transcription of the retroviral RNA genome and integration of the DNA provirus into the host genome, host machinery is used for viral gene expression along with viral proteins and RNA regulatory elements. Here, we discuss co-transcriptional and posttranscriptional regulation of retroviral gene expression, comparing simple and complex retroviruses. Cellular RNA polymerase II synthesizes full-length...

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