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Article

Risk and resilience: genetic and environmental influences on development of the stress response.

Depression and anxiety - 1 Jan 2009

Gillespie Charles F, Phifer Justine, Bradley Bekh, Ressler Kerry J

Abstract excerpt

Exposure to stressful events during development has consistently been shown to produce long-lasting alterations in the hypothalamic-pituitary-adrenal (HPA) axis, which may increase vulnerability to disease, including posttraumatic stress disorder and other mood and anxiety disorders. Recently reported genetic association studies indicate that these effects may be mediated, in part, by genexenvironment...

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Source

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Identifiers

PMID: 19750552
DOI: 10.1002/da.20605
PMCID: PMC2852579

Genes

CRHR1
FKBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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