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Article

Detection of EGFR T790M in a Large Amount of Malignant Ascites Cellblock.

Gan to kagaku ryoho. Cancer & chemotherapy - 1 Aug 2018

Ishioka Kota, Sasada Shinji, Ohgino Keiko, Sakai Tetsuya, Takahashi Saeko, Xu Chieko, Sugihara Kai, Nakamura Morio

Abstract excerpt

Osimertinib is a highly active agent for patients with progression of lung cancer despite epidermal growth factor receptor (EGFR)tyrosine kinase inhibitor treatment. This resistance is usually due to EGFR exon 20 T790M mutation, which can be detected by repeat biopsy. We report a case in which EGFR exon 20 T790M mutation was detected by repeat ascitic fluid examination. A 71-year-old woman with lung...

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Identifiers

PMID: 30158416

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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