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Article

First and repeat rebiopsy for detecting EGFR T790M mutation in non-small-cell lung cancer: CS-Lung-003 prospective observational registry study.

Journal of cancer research and clinical oncology - 1 Aug 2022

Kudo Kenichiro, Nishii Kazuya, Makimoto Go, Ishikawa Nobuhisa, Tsubata Yukari, Kodani Masahiro, Fujimoto Nobukazu, Yamasaki Masahiro, Kubota Tetsuya, Takigawa Nagio, Fujitaka Kazunori, Kanaji Nobuhiro, Shibayama Takuo, Itano Junko, Ando Chihiro, Hotta Katsuyuki, Kiura Katsuyuki

Abstract excerpt

PURPOSE: Osimertinib is still essential for the treatment of epidermal growth factor receptor (EGFR)-T790M-positive non-small-cell lung cancer (NSCLC) even in a relapsed setting, which suggests the importance of rebiopsy. The clinical value of repeat rebiopsy in patients with NSCLC who are T790M-negative on a first rebiopsy remains unclear. In this study, we examined the status of the first rebiopsy and evaluated...

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Aniline Compounds
Biopsy
Carcinoma, Non-Small-Cell Lung
Drug Resistance, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Observational Studies as Topic

Protein Kinase Inhibitors

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PMID: 35386002
DOI: 10.1007/s00432-021-03893-z

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