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Article

Cytogenetic abnormalities in systemic mastocytosis: WHO subcategory-specific incidence and prognostic impact among 348 informative cases.

American journal of hematology - 1 Dec 2018

Shah Sahrish, Pardanani Animesh, Elala Yoseph C, Lasho Terra L, Patnaik Mrinal M, Reichard Kaaren K, Hanson Curtis A, Ketterling Rhett P, Tefferi Ayalew

Abstract excerpt

The World Health Organization (WHO) system lists five morphological categories of systemic mastocytosis (SM): indolent (ISM), smoldering, SM with an associated hematological neoplasm (SM-AHN), aggressive (ASM) and mast cell leukemia (MCL). Recent studies have highlighted the prognostic importance of mutations in SM, including ASXL1, RUNX1, and SRSF2. In contrast, information on incidence of cytogenetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30152525
DOI: 10.1002/ajh.25265

Genes

ASXL1
RUNX1
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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