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Article

Systemic mastocytosis in adults: 2013 update on diagnosis, risk stratification, and management.

American journal of hematology - 1 Jul 2013

Pardanani Animesh

Abstract excerpt

DISEASE OVERVIEW: Systemic mastocytosis (SM) results from a clonal proliferation of abnormal mast cells (MC) in one or more extracutaneous organs. DIAGNOSIS: The major criterion is presence of multifocal clusters of morphologically abnormal MC in the bone marrow. Minor diagnostic criteria include elevated serum tryptase level, abnormal MC expression of CD25 and/or CD2, and presence of KITD816V. RISK...

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Adrenal Cortex Hormones
CD2 Antigens
Imatinib Mesylate
Interleukin-2 Receptor alpha Subunit
Mast Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mastocytosis, Systemic

Palliative Care

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Identifiers

PMID: 23720340
DOI: 10.1002/ajh.23459

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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