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Article

Moving toward molecular classification of diffuse gliomas in adults

29 Oct 2012

Abstract excerpt

Diffuse gliomas are a heterogenous group of neoplasms traditionally classified as grades II to IV based on histologic features, and with prognosis determined mainly by histologic grade and pretreatment clinical factors. Our understanding of the molecular basis of glioma initiation, tumor progression, and treatment failure is rapidly evolving. A molecular profile of diffuse gliomas is emerging. Studies evaluating...

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PMID: 23109653
DOI: 10.1212/wnl.0b013e318271f7cb

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