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Article

TP53 Mutation and Complex Karyotype Portends a Dismal Prognosis in Patients With Mantle Cell Lymphoma.

Clinical lymphoma, myeloma & leukemia - 1 Nov 2018

Obr Aleš, Procházka Vít, Jirkuvová Andrea, Urbánková Helena, Kriegova Eva, Schneiderová Petra, Vatolíková Michaela, Papajík Tomáš

Abstract excerpt

BACKGROUND: TP53 mutation (TP53mut) and a complex karyotype (CK) were shown to be predictors of poor outcome in mantle-cell lymphoma (MCL). In this study we examined the combined effect of both of these risk factors. PATIENTS AND METHODS: Patients diagnosed with MCL between January 2000 and December 2014 (n = 74) were evaluated. Forty-eight of them had available material for TP53 and cytogenetic examination. We...

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Identifiers

PMID: 30146365
DOI: 10.1016/j.clml.2018.07.282

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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