Article
TP53 mutation heterogeneity reveals distinct prognoses in mantle cell lymphoma.
Annals of hematology - 21 Jan 2026
Liu Shuozi, Zhou Shaowei, Zhang Weilong, Wang Jing, Wang Lingli, Li Chunyuan, Chen Yingtong, Qi Wenxin, Yang Ping, Jing Hongmei
Abstract excerpt
Mantle cell lymphoma (MCL) is an uncommon and aggressive type of B-cell non-Hodgkin lymphoma, wherein TP53 mutations play a critical role. This study analyzed the effect of different TP53 mutations on the clinical characteristics and prognosis of patients with MCL. TP53 sequencing data and clinical and prognostic information were collected from 215 patients with MCL treated at Peking University Third Hospital...
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