Article
Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes.
Lipids in health and disease - 25 Aug 2018
Feng Yue-Hua, Zheng Lu, Wei Jiang, Yu Miao-Mei, Zhang Jun, Luo Guang-Hua, Xu Ning
Abstract excerpt
BACKGROUND: Scavenger receptor BI (SR-BI) is a classic high-density lipoprotein (HDL) receptor, which mediates selective lipid uptake from HDL cholesterol esters (HDL-C). Apolipoprotein M (ApoM), as a component of HDL particles, could influence preβ-HDL formation and cholesterol efflux. The aim of this study was to determine whether SR-BI deficiency influenced the expression of ApoM. METHODS: Blood samples and...
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