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Article

Mutational analyses for product specificity of YjiC towards α-mangostin mono-glucoside.

Enzyme and microbial technology - 1 Nov 2018

Kim Tae-Su, Le Tuoi Thi, Nguyen Hue Thi, Cho Kye Woon, Sohng Jae Kyung

Abstract excerpt

Glycosyltransferases (GTs) are key enzymes for the post-modification of secondary metabolites in drug development processes. In our prior research, an one-pot enzymatic system produced α-mangostin 3,6-di-O-β-D-glucopyranoside (Mg1) at a higher proportion using wild-type glycosyltransferase (YjiC) but α-mangostin 3-O-β-D-glucopyranoside (Mg2) exhibited markedly higher anti-bacterial activities. This study focuses...

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Identifiers

PMID: 30143203
DOI: 10.1016/j.enzmictec.2018.08.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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