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Article

Rational design of a β-glycosidase with high regiospecificity for triterpenoid tailoring.

Chembiochem : a European journal of chemical biology - 23 Mar 2015

Park Sang Jin, Choi Jung Min, Kyeong Hyun-Ho, Kim Song-Gun, Kim Hak-Sung

Abstract excerpt

Triterpenoids with desired glycosylation patterns have attracted considerable attention as potential therapeutics for inflammatory diseases and various types of cancer. Sugar-hydrolyzing enzymes with high substrate specificity would be far more efficient than other methods for the synthesis of such specialty triterpenoids, but they are yet to be developed. Here we present a strategy to rationally design a...

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PMID: 25703680
DOI: 10.1002/cbic.201500004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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