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Article

Memory Impairment Induced by Borna Disease Virus 1 Infection is Associated with Reduced H3K9 Acetylation

1 Jan 2018

Abstract excerpt

BACKGROUND/AIMS: Borna disease virus 1 (BoDV-1) infection induces cognitive impairment in rodents. Emerging evidence has demonstrated that Chromatin remodeling through histone acetylation can regulate cognitive function. In the present study, we investigated the epigenetic regulation of chromatin that underlies BoDV-1-induced cognitive changes in the hippocampus. METHODS: Immunofluorescence assay was applied to...

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PMID: 30138929
DOI: 10.1159/000492890

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