Article
HLA-DQB1 DPB1 alleles in Japanese patients with adult-onset Still's disease.
Modern rheumatology - 1 Sept 2019
Fujita Yuya, Furukawa Hiroshi, Asano Tomoyuki, Sato Shuzo, Yashiro Furuya Makiko, Kobayashi Hiroko, Watanabe Hiroshi, Suzuki Eiji, Koga Tomohiro, Shimizu Toshimasa, Ueki Yukitaka, Eguchi Katsumi, Tsuchiya Naoyuki, Kawakami Atsushi, Migita Kiyoshi
Abstract excerpt
Objective: HLA class II alleles are major determinants of genetic predisposition to rheumatic diseases. Predisposing effects of HLA had been suggested in AOSD, however, ethnic differences may account for variations in AOSD association with HLA. We determined the contribution of HLA-DQB1, DPB1 alleles to susceptibility to Adult-onset Still's disease (AOSD) in the Japanese population. Methods: HLA-DQB1 and DPB1...
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