Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of HLA-DRB1 genotype with younger age onset and elder age onset rheumatoid arthritis in Japanese populations.

Medicine - 1 Nov 2019

Oka Shomi, Furukawa Hiroshi, Shimada Kota, Hashimoto Atsushi, Komiya Akiko, Tsunoda Shinichiro, Saisho Koichiro, Tsuchiya Naoyuki, Katayama Masao, Shinohara Satoshi, Matsui Toshihiro, Fukui Naoshi, Sano Hajime, Migita Kiyoshi, Tohma Shigeto

Abstract excerpt

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by joint destructions and human leukocyte antigen (HLA)-DRB1 is an important genetic risk factor for RA and influences the phenotype of RA. The clinical features of elder age onset RA (EORA) were known to be different from those of younger age onset RA (YORA). Previous studies reported the different association pattern of DRB1 alleles with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Alleles

Share to Arthritis, Rheumatoid

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to HLA-DRB1 Chains

Source

Open in PubMed Open full text

Identifiers

PMID: 31770283
DOI: 10.1097/MD.0000000000018218
PMCID: PMC6890270

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of HLA-DRB1 genotype with younger age onset and elder age onset rheumatoid arthritis in Japanese populations.PMID 31770283Read ↗

Shared epitope and radiologic progression are less prominent in elderly onset RA than young onset RA.Semantic proximity Read ↗

HLA-DRB1 genes and patients with late onset rheumatoid arthritis.Semantic proximity Read ↗

Associations between HLA-DRB1, RANK, RANKL, OPG, and IL-17 genotypes and disease severity phenotypes in Japanese patients with early rheumatoid arthritis.Semantic proximity Read ↗

The relationship between HLA-DRB1 alleles and disease subsets of rheumatoid arthritis in Japanese.Semantic proximity Read ↗

Effects of HLA-DRB1 alleles on susceptibility and clinical manifestations in Japanese patients with adult onset Still's disease.Semantic proximity Read ↗

HLA-DRB1 shared epitope allele polymorphisms and rheumatoid arthritis: a systemic review and meta-analysis.Semantic proximity Read ↗

The association of HLA-DRB1 alleles with rheumatoid arthritis in the Chinese Shantou population: a follow-up study.Semantic proximity Read ↗

Positive and negative association of HLA-DR genotypes with Japanese rheumatoid arthritis.Semantic proximity Read ↗

HLA-DRB1 genes and disease severity in rheumatoid arthritis in Turkey.Semantic proximity Read ↗

HLA-DRB1 allele association with rheumatoid arthritis susceptibility and severity in Syria.Semantic proximity Read ↗

HLA-DRB1 genotype associations in 793 white patients from a rheumatoid arthritis inception cohort: frequency, severity, and treatment bias.Semantic proximity Read ↗

Lack of association of HLA-DRB1 genotype with radiologic progression in Japanese patients with early rheumatoid arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.