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Article

Responsiveness to acidity via metal ion regulators mediates virulence in the gastric pathogen Helicobacter pylori

4 Jun 2004

Abstract excerpt

The virulence of pathogenic bacteria is dependent on their adaptation to and survival in the stressful conditions encountered in their hosts. Helicobacter pylori exclusively colonizes the acid stomach of primates, making it an ideal study model. Little is known about how H. pylori responds to the moderately acidic conditions encountered at its colonization site, the gastric mucus layer. Thus, we compared gene...

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Identifiers

PMID: 15228539
DOI: 10.1111/j.1365-2958.2004.04137.x

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