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Article

Tau protein aggregation is associated with cellular senescence in the brain

20 Aug 2018

Abstract excerpt

Tau protein accumulation is the most common pathology among degenerative brain diseases, including Alzheimer's disease (AD), progressive supranuclear palsy (PSP), traumatic brain injury (TBI), and over twenty others. Tau-containing neurofibrillary tangle (NFT) accumulation is the closest correlate with cognitive decline and cell loss (Arriagada, Growdon, Hedley-Whyte, & Hyman, ), yet mechanisms mediating tau...

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PMID: 30126037
DOI: 10.1111/acel.12840

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