Article
Genetic polymorphisms in candidate genes are not associated with increased vincristine-related peripheral neuropathy in Arab children treated for acute childhood leukemia: a single institution study.
Pharmacogenetics and genomics - 1 Aug 2018
Zgheib Nathalie K, Ghanem Khaled M, Tamim Hani, Aridi Carole, Shahine Randa, Tarek Nidale, Saab Raya, Abboud Miguel R, El-Solh Hassan, Muwakkit Samar A
Abstract excerpt
OBJECTIVE: The aim of this study was to evaluate the potential association between candidate genetic polymorphisms and vincristine-related peripheral neuropathy in Arab children with acute lymphoblastic leukemia (ALL). PATIENTS AND METHODS: This is a retrospective evaluation of 133 Arab children treated for ALL at the Children's Cancer Center of Lebanon. Incidence and severity of, as well as the timing (in weeks)...
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