Article
Isocitrate dehydrogenase mutations in defining the biology of and supporting clinical decision making in glioblastoma.
Ideggyogyaszati szemle - 30 Jul 2018
Kálovits Ferenc, Tompa Márton, Nagy Ádám, Kálmán Bernadette
Abstract excerpt
BACKGROUND AND PURPOSE: Oncogenesis is related to a sequential accumulation of somatic mutations. Comprehensive characterizations of the genomic landscapes have been completed recently for several tumors, glioblastoma being among the first ones. Our own translational research studies have been focused on defining molecular subtypes of glioblastoma in the clinical setting because of an expected prognostic and...
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