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Article

Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes.

BMC cancer - 14 Aug 2018

Kucherlapati Melanie

Abstract excerpt

BACKGROUND: Uncontrolled replication is a process common to all cancers facilitated by the summation of changes accumulated as tumors progress. The aim of this study was to examine small groups of genes with known biology in replication and repair at the transcriptional and genomic levels, correlating alterations with survival in uveal melanoma tumor progression. Selected components of Pre-Replication,...

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Topics

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Share to Disease-Free Survival
Share to DNA Copy Number Variations
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30107825
DOI: 10.1186/s12885-018-4705-y
PMCID: PMC6092802

Genes

CIZ1
FEN1
LIG1
MLH3
PCNA
ATRIP
CDC45
HUS1
MCM10
MCM2
MCM4
MCM5
MSH6
POLD1
POLE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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