Article
Mutational landscape in Uveal Melanoma.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology - 1 Jan 2000
Mastronikolis Stylianos, Adamopoulou Maria, Papouliakos Sotirios, Manoli Arezina, Katsinis Spyros, Makri Olga, Monastirioti Antonella Effrosyni, Tsiambas Evangelos, Georgakopoulos Constantinos
Abstract excerpt
Gross chromosomal and specific gene alterations are genetic aspects that are involved in rise, progression, and metastatic expansion of malignances. Concerning Uveal melanoma (UM), a variety of chromosome and gene functional and numerical imbalances in crucial molecular pathways such as cell cycle regulation, signaling transduction, apoptosis or angiogenesis have been identified and explained. UM is the most...
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