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Article

Epithelial-to-mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition.

The Journal of pathology - 1 Dec 2018

McCorry Amy Mb, Loughrey Maurice B, Longley Daniel B, Lawler Mark, Dunne Philip D

Abstract excerpt

The process of epithelial-to-mesenchymal transition (EMT) in cancer is a well-described process whereby epithelial tumour cells undergo molecular/phenotypic changes and transition to a mesenchymal biology. To aid in the transcriptional characterisation of this process, gene expression signatures have been developed that attribute a relative EMT score to samples in a given cohort. We demonstrate how such EMT...

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Identifiers

PMID: 30105762
DOI: 10.1002/path.5155
PMCID: PMC6282832

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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