B-1a Cell Development in Splenectomized Neonatal Mice.

doi:10.3389/fimmu.2018.01738

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Article

B-1a Cell Development in Splenectomized Neonatal Mice.

Frontiers in immunology - 1 Jan 2018

Pedersen Gabriel K, Li Xiaohong, Khoenkhoen Sharesta, Ádori Monika, Beutler Bruce, Karlsson Hedestam Gunilla B

Abstract excerpt

B-1a cells are mainly generated from fetal liver progenitor cells, peri- and neonatally. The developmental steps and anatomical sites required for these cells to become mature B-1a cells remain elusive. We recently described a phenotypically distinct transitional B cell subset in the spleen of neonatal mice that generated B-1a cells when adoptively transferred. This, in combination with findings demonstrating...

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Identifiers

PMID: 30105023
DOI: 10.3389/fimmu.2018.01738
PMCID: PMC6077197

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.