Article
Phenotypically distinct B cell development pathways map to the three B cell lineages in the mouse.
Proceedings of the National Academy of Sciences of the United States of America - 18 Apr 2006
Tung James W, Mrazek Matthew D, Yang Yang, Herzenberg Leonard A, Herzenberg Leonore A
Abstract excerpt
A recent article by Montecino-Rodriguez et al. [Montecino-Rodriguez, E., Leathers, H. & Dorshkind, K. (2006) Nat. Immunol.7, 293-301] has distinguished the early progenitors for B-1 cells, which principally develop in neonates, from early progenitors for B-2 cells, which principally develop in adult bone marrow. Here we introduce syndecan-1 (CD138) and MHC class II (I-A) as markers of early B cell development...
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