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Article

Enrichment and characterization of uncommitted B-cell precursors from fetal liver at day 12 of gestation.

The EMBO journal - 1 Feb 1992

Cumano A, Paige C J

Abstract excerpt

We describe an assay system that allows precursor cells, uncommitted for heavy and light chain immunoglobulin expression, to develop into B lymphocytes that can differentiate to antibody-producing cells. Some precursors have the immunoglobulin loci in germ-line configuration. Approximately 200-1500 precursor cells are present in one fetal liver by day 12 of gestation; they express the surface marker AA4.1. Most...

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Identifiers

PMID: 1537338
DOI: 10.1002/j.1460-2075.1992.tb05091.x
PMCID: PMC556491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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