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Article

Vocalisation as a Viable Assessment for Phenotyping Minipigs Transgenic for the Huntington Gene?

Journal of Huntington's disease - 1 Jan 2018

Rieke Lorena, Schubert Robin, Matheis Tamara, Muratori Lisa M, Motlik Jan, Schramke Sarah, Fels Michaela, Kemper Nicole, Schuldenzucker Verena, Reilmann Ralf

Abstract excerpt

BACKGROUND: Large animal models, such as the transgenic (tg) Huntington disease (HD) minipig, have been proposed to improve translational reliability and assessment of safety, efficacy and tolerability in preclinical studies. Minipigs are characterised by high genetic homology and comparable brain structures to humans. In addition, behavioural assessments successfully applied in humans could be explored in...

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Identifiers

PMID: 30103340
DOI: 10.3233/JHD-170284

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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