Article
Speech Biomarkers in Huntington's Disease: A Longitudinal Follow-Up Study in Premanifest Mutation Carriers.
Journal of Huntington's disease - 1 Jan 2024
Saft Carsten, Jessen Julia, Hoffmann Rainer, Lukas Carsten, Skodda Sabine
Abstract excerpt
Speech alterations have been reported in manifest Huntington's disease (HD) and premanifest mutation carriers (preHD). The aim of our study was to explore these alterations in preHD and whether they can be used as biomarkers. 13 preHD mutation carriers performed reading task, sustained phonation task and syllable repetition tasks at baseline and after 21 months, as well as clinical examination and MRI. Syllable...
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