Article
Spectrofluorometric genotyping of single nucleotide polymorphisms using carbon dots as fluorophores.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy - 5 Jan 2019
Motaghi Hasan, Mehrgardi Masoud Ayatollahi
Abstract excerpt
In the present manuscript, a new spectrofluorometric method for the genotyping of various single nucleotide polymorphisms (SNPs) using carbon dots (CDs) is investigated. For the construction of the assay, thiolated probe DNA is self-assembled on a gold surface via sulfur‑gold chemistry and afterward, the probe is partially hybridized with a longer target DNA strand. Subsequently, the unhybridized section of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
