Article
Analysis of TGCA data reveals genetic and epigenetic changes and biological function of MUC family genes in colorectal cancer.
Future oncology (London, England) - 1 Dec 2019
Jiang Zhipeng, Wang Huashe, Li Liang, Hou Zehui, Liu Wei, Zhou Taicheng, Li Yingru, Chen Shuang
Abstract excerpt
Aim: Few studies focused on functions and regulatory networks of MUC family members in colorectal cancer based on comprehensive analysis of online database. Materials & methods: Copy number variation, methylation, pathway analysis and drug influence on MUC expression were analyzed based on The Cancer Genome Atlas and GTEx database. Results: Copy number variation analysis showed MUC heterozygous amplification and...
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