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Article

Characterization of Drosophila ATPsynC mutants as a new model of mitochondrial ATP synthase disorders.

PloS one - 1 Jan 2018

Lovero Domenica, Giordano Luca, Marsano René Massimiliano, Sanchez-Martinez Alvaro, Boukhatmi Hadi, Drechsler Maik, Oliva Marta, Whitworth Alexander J, Porcelli Damiano, Caggese Corrado

Abstract excerpt

Mitochondrial disorders associated with genetic defects of the ATP synthase are among the most deleterious diseases of the neuromuscular system that primarily manifest in newborns. Nevertheless, the number of established animal models for the elucidation of the molecular mechanisms behind such pathologies is limited. In this paper, we target the Drosophila melanogaster gene encoding for the ATP synthase subunit...

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Identifiers

PMID: 30096161
DOI: 10.1371/journal.pone.0201811
PMCID: PMC6086398

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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