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A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish

23 Jul 2022

Abstract excerpt

Mitochondria are a dynamic eukaryotic innovation that play diverse roles in biology and disease. The mitochondrial genome is remarkably conserved in all vertebrates, encoding the same 37-gene set and overall genomic structure, ranging from 16,596 base pairs (bp) in the teleost zebrafish (Danio rerio) to 16,569 bp in humans. Mitochondrial disorders are amongst the most prevalent inherited diseases, affecting...

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PMID: 35893052
DOI: 10.3390/genes13081317

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