Article
Single-subject classification of presymptomatic frontotemporal dementia mutation carriers using multimodal MRI.
NeuroImage. Clinical - 1 Jan 2018
Feis Rogier A, Bouts Mark J R J, Panman Jessica L, Jiskoot Lize C, Dopper Elise G P, Schouten Tijn M, de Vos Frank, van der Grond Jeroen, van Swieten John C, Rombouts Serge A R B
Abstract excerpt
Background: Classification models based on magnetic resonance imaging (MRI) may aid early diagnosis of frontotemporal dementia (FTD) but have only been applied in established FTD cases. Detection of FTD patients in earlier disease stages, such as presymptomatic mutation carriers, may further advance early diagnosis and treatment. In this study, we aim to distinguish presymptomatic FTD mutation carriers from...
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