Article
White matter microstructure alterations in frontotemporal dementia: Phenotype-associated signatures and single-subject interpretation.
Brain and behavior - 1 Feb 2022
McKenna Mary Clare, Tahedl Marlene, Murad Aizuri, Lope Jasmin, Hardiman Orla, Hutchinson Siobhan, Bede Peter
Abstract excerpt
BACKGROUND: Frontotemporal dementias (FTD) include a genetically heterogeneous group of conditions with distinctive molecular, radiological and clinical features. The majority of radiology studies in FTD compare FTD subgroups to healthy controls to describe phenotype- or genotype-associated imaging signatures. While the characterization of group-specific imaging traits is academically important, the priority of...
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