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Article

Epigenome-wide DNA methylation regulates cardinal pathological features of psoriasis

9 Aug 2018

Abstract excerpt

BACKGROUND: Psoriasis is a chronic inflammatory autoimmune skin disorder. Several studies suggested psoriasis to be a complex multifactorial disease, but the exact triggering factor is yet to be determined. Evidences suggest that in addition to genetic factors, epigenetic reprogramming is also involved in psoriasis development. Major histopathological features, like increased proliferation and abnormal...

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PMID: 30092825
DOI: 10.1186/s13148-018-0541-9

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