Article
Integrative methylome and transcriptome analysis to dissect key biological pathways for psoriasis in Chinese Han population.
Journal of dermatological science - 1 Sept 2018
Tang Lili, Cheng Yuyan, Zhu Caihong, Yang Chao, Liu Lu, Zhang Yuanjing, Wen Leilei, Zhang Xuejun, Zhou Fusheng, Yang Sen
Abstract excerpt
BACKGROUND: Recent studies have revealed that DNA methylation (DNAm) could modulate gene expression in psoriasis (Ps). However, the relationship between whole-genome DNAm and gene expression in Ps has not been studied yet. OBJECTIVES: To better characterize the relationship between DNAm and gene expression, and to identify biological pathways triggered by changes in methylation involved in the pathogenesis of Ps....
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