Article
Epigenetic and Transcriptional Regulatory Networks Underlying Psoriasis Pathogenesis.
The American journal of pathology - 1 Jun 2026
Singh Hemraj, Taliyan Rajeev
Abstract excerpt
Psoriasis is a chronic, immune-mediated dermatologic disorder characterized by the hyperproliferation of keratinocytes and dysregulated immune signaling. Although genome-wide association studies have identified susceptibility loci, the multifactorial nature of the disease underlines the importance of nongenetic regulatory mechanisms. Among these epigenetic modifications are those that critically link genetic...
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