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Genome-wide DNA methylation of Munro’s microabscess reveals the epigenetic regulation in the pathogenesis of psoriasis

8 Dec 2022

Abstract excerpt

Introduction: Munro's microabscess is a typical pathological feature in the early psoriatic lesion, mainly characterized by the accumulation of neutrophils in the epidermis. DNA methylation microenvironment of Munro's microabscess and the crosstalk with transcription and its effect on neutrophils have not yet been revealed. Methods: Performed genome-wide DNA methylation analysis and further differential...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36569916
DOI: 10.3389/fimmu.2022.1057839

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