Article
Epigenetics in the pathogenesis and pathophysiology of psoriasis vulgaris.
Journal of drugs in dermatology : JDD - 1 Feb 2014
Trowbridge Ryan M, Pittelkow Mark R
Abstract excerpt
Epigenetic phenomena, including DNA methylation, histone modification, and genetic regulation by miRNAs, are potentially heritable genetic regulatory changes that are not attributed to direct alterations in the DNA sequence of base pairs. They may explain the link between psoriasis risk alleles and disease development, as alleles possess various potentials to undergo epigenetic modification. Multiple genes...
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