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Article

Oncological and genetic factors impacting PDX model construction with NSG mice in pancreatic cancer.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Jan 2019

Guo Shiwei, Gao Suizhi, Liu Rendong, Shen Jing, Shi Xiaohan, Bai Sijia, Wang Huan, Zheng Kailian, Shao Zhuo, Liang Chuanyu, Peng Siying, Jin Gang

Abstract excerpt

A patient-derived xenograft (PDX) approach, which relies on direct transplantation of tumor specimens into an immunocompromised animal, is a commonly used method for investigating tumor therapy predictions in vivo. This study evaluated influencing factors, including clinical, oncological, and genetic variables, for a pancreatic PDX model in mice. Tumor specimens were obtained from 121 patients with pancreatic...

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Share to Carcinoma, Pancreatic Ductal
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 30091943
DOI: 10.1096/fj.201800617R

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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