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Establishment and Thorough Characterization of Xenograft (PDX) Models Derived from Patients with Pancreatic Cancer for Molecular Analyses and Chemosensitivity Testing

8 Dec 2023

Abstract excerpt

Patient-derived xenograft (PDX) tumor models are essential for identifying new biomarkers, signaling pathways and novel targets, to better define key factors of therapy response and resistance mechanisms. Therefore, this study aimed at establishing pancreas carcinoma (PC) PDX models with thorough molecular characterization, and the identification of signatures defining responsiveness toward drug treatment. In...

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Cancer Cells and Metastasis
Cancer Genomics and Diagnostics
Pancreatic and Hepatic Oncology Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38136299
DOI: 10.3390/cancers15245753

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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