Article
The role of ABC transporters' gene polymorphism in the etiology of intrahepatic cholestasis of pregnancy.
Ginekologia polska - 1 Jan 2018
Piątek Krzysztof, Kurzawińska Grażyna, Magiełda Justyna, Drews Krzysztof, Barlik Magdalena, Malewski Zbyszko, Ożarowski Marcin, Maciejewska Małgorzata, Seremak-Mrozikiewicz Agnieszka
Abstract excerpt
OBJECTIVES: The etiology of intrahepatic cholestasis of pregnancy (ICP) involves environmental, hormonal and genetic factors. It is thought that ICP may be related to the polymorphic variants of several genes involved in the metabolism and transport of bile acids (BA). The goal of our study was to evaluate the possible role of genetic polymorphic variants of ABC transporters in patients with ICP. MATERIAL AND...
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