Article
Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer.
Cancer genomics & proteomics - 1 Jan 2000
Gottschling Sandra, Schnabel Philipp A, Herth Felix J F, Herpel Esther
Abstract excerpt
Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in Western countries. Despite novel molecular therapies, the majority of patients with advanced or metastatic disease show rapid progression and a median survival time of not more than 18 months. In the last decade, there has been increasing evidence that cancer stem cells (CSC) play a pivotal role in drug resistance, tumour...
Topics
- AC133 Antigen
- ATP Binding Cassette Transporter, Subfamily G, Member 2
- ATP-Binding Cassette Transporters
- Animals
- Antigens, CD
- Biomarkers, Tumor
- Carcinoma, Non-Small-Cell Lung
- Cell Transformation, Neoplastic
- Drug Resistance, Neoplasm
- Epithelium