Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer.

Cancer genomics & proteomics - 1 Jan 2000

Gottschling Sandra, Schnabel Philipp A, Herth Felix J F, Herpel Esther

Abstract excerpt

Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related death in Western countries. Despite novel molecular therapies, the majority of patients with advanced or metastatic disease show rapid progression and a median survival time of not more than 18 months. In the last decade, there has been increasing evidence that cancer stem cells (CSC) play a pivotal role in drug resistance, tumour...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to AC133 Antigen
Share to Antigens, CD
Share to ATP Binding Cassette Transporter, Subfamily G, Member 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Epithelium

Share to Glycoproteins

Share to Neoplastic Stem Cells

Share to Survival Analysis

Source

Identifiers

PMID: 22990107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Are we missing the target? Cancer stem cells and drug resistance in non-small cell lung cancer.PMID 22990107Read ↗

Lung cancer stem cells: The root of resistance.Semantic proximity Read ↗

A role for cancer stem cells in drug resistance and metastasis in non-small-cell lung cancerSemantic proximity Read ↗

Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?Semantic proximity Read ↗

Targeting Lung Cancer Stem Cells: Research and Clinical ImpactsSemantic proximity Read ↗

Concise Review: Resistance to Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer: The Role of Cancer Stem CellsSemantic proximity Read ↗

At the crossroads of cancer stem cells and targeted therapy resistance.Semantic proximity Read ↗

Drug resistance and Cancer stem cellsSemantic proximity Read ↗

Drug resistance mechanisms of cancer stem-like cells and their therapeutic potential as drug targetsSemantic proximity Read ↗

The cancer stem-cell hypothesis: its emerging role in lung cancer biology and its relevance for future therapy.Semantic proximity Read ↗

Lung cancer stem cells—characteristics, phenotypeSemantic proximity Read ↗

Comprehensive review of drug resistance in mammalian cancer stem cells: implications for cancer therapySemantic proximity Read ↗

Targeting cancer stem cells for reversing therapy resistance: mechanism, signaling, and prospective agentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.