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Article

LDLR and PCSK9 Are Associated with the Presence of Antiphospholipid Antibodies and the Development of Thrombosis in aPLA Carriers.

PloS one - 1 Jan 2016

Ochoa Eguzkine, Iriondo Mikel, Manzano Carmen, Fullaondo Asier, Villar Irama, Ruiz-Irastorza Guillermo, Zubiaga Ana M, Estonba Andone

Abstract excerpt

INTRODUCTION: The identification of the genetic risk factors that could discriminate non- thrombotic from thrombotic antiphospholipid antibodies (aPLA) carriers will improve prognosis of these patients. Several human studies have shown the presence of aPLAs associated with atherosclerotic plaque, which is a known risk factor for thrombosis. Hence, in order to determine the implication of atherosclerosis in the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 26820623
DOI: 10.1371/journal.pone.0146990
PMCID: PMC4731066

Genes

LDLR
PCSK9
APOH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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