Article
Genetic determinants of arterial thrombosis in primary antiphospholipid syndrome: a systematic review.
Frontiers in immunology - 1 Jan 2026
Gavris Claudia, Sovaila Silvia, Girdan Laura, Purcarea Adrian
Abstract excerpt
Background: Primary Antiphospholipid Syndrome (PAPS) is a systemic autoimmune disorder characterized by arterial and/or venous thrombosis and obstetric morbidity. Arterial thrombosis, although less frequent than venous events, is associated with substantial morbidity and mortality. Alongside environmental and acquired factors, several genetic polymorphisms affecting coagulation, endothelial function,...
Topics
- Humans
- Antiphospholipid Syndrome
- Thrombosis
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Polymorphism, Single Nucleotide