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Article

Therapeutic potential of pancreatic PAX4-regulated pathways in treating diabetes mellitus.

Current opinion in pharmacology - 1 Dec 2018

Lorenzo Petra I, Cobo-Vuilleumier Nadia, Gauthier Benoit R

Abstract excerpt

The high prevalence of diabetes mellitus (DM) in our society, together with the fact that current treatments are only palliative and do not prevent the development of life threatening side effects, highlights the urgent need for novel therapies targeting the root cause of the disease. Independent of the etiology of DM, the definitive therapeutic approach will imply the restitution of an adequate functional β-cell...

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Source

Identifiers

PMID: 30048825
DOI: 10.1016/j.coph.2018.07.004

Genes

PAX4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Beta cell regeneration meets autoimmunity: PAX4 variants in type 1 diabetes.Semantic proximity Read ↗

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