Article
Influence of N-acetyltransferase 2 polymorphisms and clinical variables on liver function profile of tuberculosis patients.
Expert review of clinical pharmacology - 1 Mar 2024
Thomas Levin, Raju Arun Prasath, Chaithra S, Kulavalli Shrivathsa, Varma Muralidhar, Sv Chidananda Sanju, Baneerjee Mithu, Saravu Kavitha, Mallayasamy Surulivelrajan, Rao Mahadev
Abstract excerpt
BACKGROUND: Single nucleotide polymorphisms (SNPs) in the N-acetyltransferase 2 (NAT2) gene as well as several other clinical factors can contribute to the elevation of liver function test values in tuberculosis (TB) patients receiving antitubercular therapy (ATT). RESEARCH DESIGN AND METHODS: A prospective study involving dynamic monitoring of the liver function tests among 130 TB patients from baseline to...
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