Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Nonsynonymous Polymorphisms Val276Met and Gly393Ser of E2F1 Gene are Strongly Associated with Lung, and Head and Neck Cancers.

Genetic testing and molecular biomarkers - 1 Aug 2018

Singh Sanjay, Gupta Manish, Sharma Ambika, Seam Rajeev Kumar, Changotra Harish

Abstract excerpt

AIM: The early gene factor-2 (E2F), a family of transcription factors, is involved in cell cycle regulation. Deregulated expression of most of the members of the E2F family is associated with various human cancers. In this study, we investigated the association between the E2F1 genetic variants rs3213173 (C/T) (Val276Met) and rs3213176 (G/A) (Gly393Ser) with the risk of lung cancer (LC) and head and neck cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People
Share to Case-Control Studies
Share to E2F1 Transcription Factor
Share to Genetic Association Studies
Share to Head and Neck Neoplasms
Share to India
Share to Lung Neoplasms
Share to Odds Ratio

Source

Identifiers

PMID: 30036075
DOI: 10.1089/gtmb.2018.0066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Nonsynonymous Polymorphisms Val276Met and Gly393Ser of E2F1 Gene are Strongly Associated with Lung, and Head and Neck Cancers.PMID 30036075Read ↗

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

Identification of nsSNPs of transcription factor E2F1 predisposing individuals to lung cancer and head and neck cancer.Semantic proximity Read ↗

Genetic variants of cell cycle pathway genes are associated with head and neck squamous cell carcinoma in the Chinese population.Semantic proximity Read ↗

Identification of a Low-Frequency Missense Variant in E2F Transcription Factor 7 Associated with Colorectal Cancer Risk In A Chinese PopulationSemantic proximity Read ↗

The association of E2F1 and E2F2 single nucleotide polymorphisms with laryngeal squamous cell carcinoma pathomorphological features.Semantic proximity Read ↗

A functional variant at the miRNA binding site in E2F1 gene is associated with risk and tumor HPV16 status of oropharynx squamous cell carcinoma.Semantic proximity Read ↗

Genetic Polymorphism of E2F1 Influences Susceptibility to Ovarian Cancer in a Chinese Population.Semantic proximity Read ↗

HapMap-based study of the DNA repair gene ERCC2 and lung cancer susceptibility in a Chinese population.Semantic proximity Read ↗

Association of genetic polymorphisms in DNA repair genes ERCC2 Asp312Asn (rs1799793), ERCC2 Lys 751 Gln (rs13181), XRCC1 Arg399 Gln (rs25487) and XRCC3 Thr 241Met (rs861539) with the susceptibility of lung cancer in Saudi population.Semantic proximity Read ↗

MTF1 genetic variants are associated with lung cancer risk in the Chinese Han population.Semantic proximity Read ↗

Impact of COL6A4P2 gene polymorphisms on the risk of lung cancer: A case-control study.Semantic proximity Read ↗

ERCC2, ERCC1 polymorphisms and haplotypes, cooking oil fume and lung adenocarcinoma risk in Chinese non-smoking females.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.