Article
Association of genetic polymorphisms in DNA repair genes ERCC2 Asp312Asn (rs1799793), ERCC2 Lys 751 Gln (rs13181), XRCC1 Arg399 Gln (rs25487) and XRCC3 Thr 241Met (rs861539) with the susceptibility of lung cancer in Saudi population.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2022
Alsagaby Suliman, Ahmed Ahmed A, Rasheed Zafar, Althwab Sami A, Aljohani Abdullah S M, Alhumaydhi Fahad A, Alhomaidan Homaidan T, Alkhamiss Abdullah S, Alkhowailed Mohammad, Alaqeel Aqeel, Alblihed Mohamd A, Alrehaili Jihad, Fernández Nelson, Abdulmonem Waleed Al
Abstract excerpt
This study demonstrated the association of polymorphisms in ERCC2 (Asp312Asn) rs1799793, ERCC2 (Lys751Gln) rs13181, XRCC1 (Arg399Gln) rs25487 and XRCC3(Thr241Met) rs861539 polymorphisms with a susceptibility of lung cancer (LC) onset in the Saudi population. The study was performed on 134 LC patients and 270 controls. The data revealed that there was no significant association of LC with subtype squamous cell...