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Article

Combined effects of E2F1 and E2F2 polymorphisms on risk and early onset of squamous cell carcinoma of the head and neck.

Molecular carcinogenesis - 1 Oct 2012

Lu Meixia, Liu Zhensheng, Yu Hongping, Wang Li-E, Li Guojun, Sturgis Erich M, Johnson David G, Wei Qingyi

Abstract excerpt

Deregulated expression of most members of the E2F family has been detected in many human cancers. We examined the association of common single nucleotide polymorphisms (SNPs) of E2F transcription factors 1 and 2 (E2F1 and E2F2) with risk of squamous cell carcinoma of the head and neck (SCCHN) in 1,096 SCCHN patients and 1,090 cancer-free controls. We genotyped 10 selected SNPs in E2F1 and E2F2, including those at...

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Identifiers

PMID: 22344756
DOI: 10.1002/mc.21882
PMCID: PMC3370129

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